Formation and Stability of Synaptic Receptor Domains: Supplemental Material
نویسندگان
چکیده
A summary of experimental materials and methods is presented in Sec. S1. Section S2 provides supplementary information on Eqs. (1) and (2) of the main text, and Sec. S3 discusses in greater detail our reaction kinetics for the formation and stability of synaptic receptor domains. Finally, Secs. S4 and S5 provide supplementary information pertaining to the simulations of the steady-state and plasticity of synaptic receptor domains.
منابع مشابه
Formation and stability of synaptic receptor domains.
Neurotransmitter receptor molecules, concentrated in postsynaptic domains along with scaffold and a number of other molecules, are key regulators of signal transmission across synapses. Combining experiment and theory, we develop a quantitative description of synaptic receptor domains in terms of a reaction-diffusion model. We show that interactions between only receptors and scaffolds, togethe...
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